The habitat of Lithops lesliei subsp. lesliei is grassland or gravelly open ground on flats and slopes. In spite of a habitat of sparse vegetation in the western parts of its large distribution area in inland South Africa, this tiny stone plant is often not spotted among the small real stones and grass. Bigger rocks, shrubs and grass may provide shelter against the elements and human prowlers seeking it.
The plant is sought after and from a survival point of view, maybe too often found. This plant is in demand among succulent gardeners as well as traditional healers who use the plant for its medicinal properties. This Lithops is said to be reducing in numbers in nature due to harvesting and development, but may be increasing in cultivated numbers (Smith, et al, 1998; Wikipedia).