Lycium ferocissimum is a much-branched, spiny and rigid shrub that grows to 2 m in height. Young stems are green, becoming whitish as they age. Side branchlets are often horizontal and spiny. The stout spines are between 5 cm and 7 cm long. Lycium trees and shrubs (or shrublets) are generally known as honey thorns.
The distribution of this species lies from Namaqualand through the Karoo to the Eastern Cape. The plant is often found on dry, stony flats and lowland areas among scrub vegetation of variable composition. The plant was unfortunately introduce in Australia where it has become a weed (Vlok and Schutte-Vlok, 2010; Coates Palgrave, 2002).